Similar to keratoconus and PMD, keratoglobus is a bulging caused by a thinning of the cornea. This weakens the structure and allows the pressure within the eye to push the cornea outwards into a cone shape, which gives the condition its name. 

Keratoconus and PMD occur due to localised areas of thinning allowing the cornea to bulge in those areas. Keratoglobus is caused by a more generalised thinning over a larger area. This means that the cornea bulges over a larger area – sometimes its entire diameter. Advanced cases may be almost hemispherical, and larger scleral lenses are probably the best, if not the only, way of correcting vision.

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